English
Next Generation Sequencing (NGS), a state-of-the-art molecular biology technique enables precise reading of human genetic code. Great advantages of NGS translate into a wide range of applications including in medical diagnostics. INVICTA Genetic Laboratory has prepared a personalized test platform called Open Frame Sequencing™ based on NGS.
Open Frame Sequencing is a universal tool that allows planning comprehensive genetic diagnosis targeted at the patient’s individual needs. Open Frame Sequencing™ allows identification of over 163,000 of all known and described mutations, over 331,000 of all exons in the human genome and examination of coding sequences of over 15,000 known genes.
The new personalized genetic platform, Open Frame Sequencing™, provides new opportunities for clinics and physicians, and expands access to tests based on the latest technologies.
Thanks to the development of molecular techniques there are more and more offers of genetic testing on the market. It is possible to examine a human genome for predispositions for thromboembolic diseases, genetic causes of male or female infertility or cancer. However, a Patient can get lost among various available panels or predetermined offers of various tests. Often it is impossible to find the specific test need to confirm genetic background of a clinically diagnosed disease or to detect a pathogenic mutation that is present in the family. INVICTA Genetic Laboratory is meeting expectations of such patients by creating a personalized genetic platform called Open Frame Sequencing™.
Open Frame Sequencing™ is a universal diagnostic tool which allows to planning comprehensive genetic diagnostics personalized for each Patient. This innovative solution is dedicated to specialists who expect a flexible approach, efficient cooperation and “tailor made” solutions in their daily work. Open Frame Sequencing is based on Next Generation Sequencing (NGS), the most advanced diagnostic technique available. NGS is currently considered a reference technique for all other techniques of DNA analysis. In Sanger method sequencing tested genes are usually read twice, where as with NGS makes each selected place is read at least 200 times.This technique also makes it possible to sequence a great number of DNA fragments at the same time.
